Frequency of Anca in Glomerulonephritis.: University of Health Sciences, Lahore, Pakistan - Nadeem Afzal - Bøger - LAP LAMBERT Academic Publishing - 9783846547564 - December 5, 2011

Frequency of Anca in Glomerulonephritis.: University of Health Sciences, Lahore, Pakistan

Nadeem Afzal

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Frequency of Anca in Glomerulonephritis.: University of Health Sciences, Lahore, Pakistan

Objectives: Current study was designed to determine the frequency of ANCA (p-ANCA and c-ANCA) in clinically diagnosed glomerulonephritis patients. Study Design: Cross-sectional analytical study. Place and Period of study: Department of Immunology, University of Health Sciences, Lahore in a period of one year. Materials and Methods: The study included 64 glomerulonephritis patients. Methodology: Levels of ANCA (MPO and PR3) were determined by ELISA technique. Results: Four (6.25%) patients showed positive reaction to myeloperoxidase [MPO] antigen while 1 (1.56%) was positive for proteinase-3 [PR3] antigen. Sero-positivity for MPO and PR3 in the patients of 40-60 years of age,was 14% and 3.6% respectively. p-value for MPO and PR3 was > 0.05 and <0.05 respectively. Conclusion: Glomerulonephritis is more related with MPO-ANCA than PR3-ANCA. The difference in levels of MPO-ANCA in different age groups was significant but it was non-significant among different genders. The difference in levels of PR3-ANCA was non-significant for both age and gender.

Media Books     Paperback Book   (Book with soft cover and glued back)
Released December 5, 2011
ISBN13 9783846547564
Publishers LAP LAMBERT Academic Publishing
Pages 60
Dimensions 150 × 4 × 226 mm   ·   99 g
Language English  

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